← Return to Forteo (teriparatide) followed by HRT: My Experience

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@tillymack

Parathyroid hormone (PTH), made by parathyroid glands in the neck, keeps blood calcium levels stable. When blood calcium level drops, the parathyroid gland releases PTH, which causes release of calcium from bones, helps the kidneys retain calcium, and boosts absorption of calcium from food. Too much PTH over time, as seen in hyperparathyroidism, can lead to increased bone resorption, weakening bones and increased fracture risk.

Forteo (teriparatide) is a lab-made fragment of PTH (amino acids 1–34) approved for osteoporosis treatment in 2002. Research in the 1970s by a British scientist showed that intermittent (short, spaced-out) dosing of PTH could stimulate bone formation in mammals. This led to the development of synthetic PTH 1–34 or teriparatide, trademarked and marketed by Eli Lilly as Forteo.

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Replies to "@tillymack Parathyroid hormone (PTH), made by parathyroid glands in the neck, keeps blood calcium levels stable...."

@mayblin Thanks so much for your excellent reply!

@mayblin I am on Teriparatide and will do the full 18 month course. Prior to this I took Forteo in 2016, one shot of Prolia and then 5 years Raloxifene . I am planning to go back on Raloxifene. It would be very helpful to Osteoprosis treatment if someone would gather research on second courses of Forteo/Teriparatide as this appears to have the least side effects and has done well for me. My endocrinologist is really pushing follow up with Evenity, but why change a good recipe? I had 13 compression fractures prior to treatment with Forteo and have not fractured since.