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Forteo (teriparatide) followed by HRT: My Experience
Osteoporosis & Bone Health | Last Active: Feb 20 8:32pm | Replies (190)Comment receiving replies
Thank you! Do you know what human parathyroid hormone does for the body, especially with regard to bones? Is human parathyroid hormone secreted normally for the benefit of bones and is this substance from Forteo adding more of the same / similar to what would naturally be there? Thanks again!
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@tillymack
Parathyroid hormone (PTH), made by parathyroid glands in the neck, keeps blood calcium levels stable. When blood calcium level drops, the parathyroid gland releases PTH, which causes release of calcium from bones, helps the kidneys retain calcium, and boosts absorption of calcium from food. Too much PTH over time, as seen in hyperparathyroidism, can lead to increased bone resorption, weakening bones and increased fracture risk.
Forteo (teriparatide) is a lab-made fragment of PTH (amino acids 1–34) approved for osteoporosis treatment in 2002. Research in the 1970s by a British scientist showed that intermittent (short, spaced-out) dosing of PTH could stimulate bone formation in mammals. This led to the development of synthetic PTH 1–34 or teriparatide, trademarked and marketed by Eli Lilly as Forteo.