My nephrologist wants me to take Jardiance for CKD?

Posted by steveutnv @steveutnv, Oct 8 10:05am

My kidney doctor says I should try taking Jardiance for my CKD. He says patients have seen good results with it, even though Jardiance use for CKD is not recommended. It's $800 with my part D deductible, so I've declined.

Has anyone here taken Jardiance for CKD?

Interested in more discussions like this? Go to the Kidney Conditions Support Group.

You may make too much money, but you might check https://www.boehringer-ingelheim.com/us/about-us/sustainable-development/our-commitment/boehringer-cares-patient-assistance-portal
"Jardiance is not recommended for the treatment of chronic kidney disease in patients with polycystic kidney disease or patients requiring or with a recent history of intravenous immunosuppressive therapy or greater than 45 mg of prednisone or equivalent for kidney disease." But it is FDA approved for chronic kidney disease otherwise. I haven't taken the medication and hope you get better responses than mine.

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Profile picture for gently @gently

You may make too much money, but you might check https://www.boehringer-ingelheim.com/us/about-us/sustainable-development/our-commitment/boehringer-cares-patient-assistance-portal
"Jardiance is not recommended for the treatment of chronic kidney disease in patients with polycystic kidney disease or patients requiring or with a recent history of intravenous immunosuppressive therapy or greater than 45 mg of prednisone or equivalent for kidney disease." But it is FDA approved for chronic kidney disease otherwise. I haven't taken the medication and hope you get better responses than mine.

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@gently thank you. I've been researching it and it appears it is approved for CKD in my situation. Now I'm trying to work my way through my Medicare part d coverage and see if it's going to cost an arm and a leg or if I can get away for a few fingers.

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Sometimes the income limits for assistance are high. Then you just wouldn't use the medicare. i sometimes travel for medications because we do pay the highest prices of anywhere in the world. But at least we can get them, if we don't need our arms or legs.
https://patient.boehringer-ingelheim.com/us/products/jardiance/type-2-diabetes/pricing#:~:text=I%20Have%20No%20Insurance%20(or,supply%20of%20JARDIANCE%20is%20%24629.43.

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My Mayo nephrologist/hematologist recommended the related medication, Farxiga, which is not part of my insurance' formulary. My local nephrologist said Jardiance is used for the same purpose. I have CKD as a part of having idiopathic immunotactoid glomerulopathy. However, my e-GFR puts me at stage 2 CKD. On the other hand, I have serious proteinuria, a hallmark of ITG. (My nephrologist writes I am at Stage 2/3 in appt. summaries.) I gather that Jardiance/Farxiga lessen proteinuria. There are about 10 of us in the world with idiopathic ITG so the efficacy of Jardiance is unknown for us.

I didn't want to start a new medication whose side effects include possible fatal skin rashes and increased urination just when my son and his family were going to be visiting. The youngest had never been to visit us and the older was 9 months old back then--we go visit them instead. My local nephrologist concurred but I suspect the topic will be part of my next appt.

I did check out the price--even with what has been good drug coverage, Jardiance was pricey. My husband has one medication that puts him over the out of pocket limit ($2000, right?) in January so he didn't flinch when I told him--until I mentioned those two side effects. I already know where the rest rooms are at almost every location we visit--stores, museums, zoos, etc. because it's a "feature" of life after gall bladder removal (done in 1977).

I shouldn't be so easily influenced by TV commercials but the singing and dancing happy diabetics in the ads was very off-putting for me. (I'm not diabetic.)

I'd also like to hear the experiences of those who take Jardiance.

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Profile picture for mnsansei @mnsansei

My Mayo nephrologist/hematologist recommended the related medication, Farxiga, which is not part of my insurance' formulary. My local nephrologist said Jardiance is used for the same purpose. I have CKD as a part of having idiopathic immunotactoid glomerulopathy. However, my e-GFR puts me at stage 2 CKD. On the other hand, I have serious proteinuria, a hallmark of ITG. (My nephrologist writes I am at Stage 2/3 in appt. summaries.) I gather that Jardiance/Farxiga lessen proteinuria. There are about 10 of us in the world with idiopathic ITG so the efficacy of Jardiance is unknown for us.

I didn't want to start a new medication whose side effects include possible fatal skin rashes and increased urination just when my son and his family were going to be visiting. The youngest had never been to visit us and the older was 9 months old back then--we go visit them instead. My local nephrologist concurred but I suspect the topic will be part of my next appt.

I did check out the price--even with what has been good drug coverage, Jardiance was pricey. My husband has one medication that puts him over the out of pocket limit ($2000, right?) in January so he didn't flinch when I told him--until I mentioned those two side effects. I already know where the rest rooms are at almost every location we visit--stores, museums, zoos, etc. because it's a "feature" of life after gall bladder removal (done in 1977).

I shouldn't be so easily influenced by TV commercials but the singing and dancing happy diabetics in the ads was very off-putting for me. (I'm not diabetic.)

I'd also like to hear the experiences of those who take Jardiance.

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@mnsansei

My husband, has a rare kidney disease . . . MGN, hovers between a 1+, 2 to 3+ protein loss in a 24-hour test, having had one Rituximab infusion in 2021 for his kidney disease and was told Farxiga would help but because of the expense, was told Jardiance would provide the same preventative benefits as Farxiga. He opted NOT to take either one because of, yes, similar cost but also because everything carries with it certain types of side effects. That one infusion he had years ago brought his proteinuria down to the 1+ range; so, if anything gets worse, his plan is to ask for another one of those, rather than starting another med on a daily basis.

Every CKD is different, obviously, and that dang infusion brings his white count down, as it's an immunosuppressant, but for him . . . new meds can be a slipperier slope sometimes.

Good luck with your decision!

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I think I'm going to try the Jardiance because my eGFR is at 29, but I'll wait until 2026 because I'd have to pay my $590 deductible if I start it now. Then I'd have to pay the annual deductible again next year (which is going up to 310.)

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Profile picture for steveutnv @steveutnv

I think I'm going to try the Jardiance because my eGFR is at 29, but I'll wait until 2026 because I'd have to pay my $590 deductible if I start it now. Then I'd have to pay the annual deductible again next year (which is going up to 310.)

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@steveutnv - My PCP cut my Metformin by half, and put me on Jardiance once my eGFR got to 42. New doc removed Metformin completely, but left Jardiance in place. EGFR had declined to 32, but has since rebounded back to 42.

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Profile picture for healthcuriosity101 @healthcuriosity101

@steveutnv - My PCP cut my Metformin by half, and put me on Jardiance once my eGFR got to 42. New doc removed Metformin completely, but left Jardiance in place. EGFR had declined to 32, but has since rebounded back to 42.

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@healthcuriosity101 thank you for that information, I'm going to try it.

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Profile picture for steveutnv @steveutnv

I think I'm going to try the Jardiance because my eGFR is at 29, but I'll wait until 2026 because I'd have to pay my $590 deductible if I start it now. Then I'd have to pay the annual deductible again next year (which is going up to 310.)

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@steveutnv A sad indication of how broken our healthcare system is. Good luck.

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I use a Jardience manufacturer coupon with my private insurance or I couldn't afford it. $125 a month

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