@consumer
I never heard of Evenity, but I did Google it. It is a protein based chemical compound with severe heart warnings. Also, protein plaque affects our brain function as we age. Estrogen helps brain function. The Evenity compound is not natural to the human body. Pure estrogen or other medications with estrogen are natural to the human body. Our bodies stop making it after menopause. However, estrogen is key in heart function when we are younger, probably due to the preparation for pregnancy. Our hearts can still function without it after menopause, but not as well. Also, I was warned that the use of estrogen for more than two years increases substantially cancer risks. I haven't seen the studies that support this information.

I will say that like any drug, every woman who uses estrogen should check for genetic predisposition for breast, ovarian, or uterine cancers. It is a gene test. Premarin has incredible potential for slowing the aging process for women.

However, our bodies' cells have something called "programmed cell death." Every cell knows when they are ready to die and let it be known by something called pain and/or discomfort. Estrogen has a way of delaying or masking that genetic trait in women, and cell death is present in all living things. But our other billions of cells are not all on board with masking or delaying cell death. So you have a conflict going on in your body, if you choose to try estrogen; the conflict may not be pleasant either.

Finally Estrogen brand name is Premarin and there is no patent for a generic. It's made by Pfizer a well respected drug manufacturer. I don't think there are enough women using Premarin to accurately predict outcomes of long-term risks.

Keep in mind that my nursing studies are slow and on going when evaluating my opinion. I am a 69 year-old older woman. While I have completed all the nursing prerequisites, I still haven't passed Nursing Physiology yet for nursing school. But I have passed five technical certifications boards and the NBCC counseling board as a graduate student, earned an associate degree in Nursing Education, and passed pathology/PBT board exam, and earned an ASCP certification.

Thanks for reading!