I had heart attack and open -heart surgery 24 years ago at the age of 56. I was given statin, blood pressure medicine and low dose aspirin until last November. I lowered my cholesterol from 210 to 115 in 5 years. I started working out with weights and exercising 3-5 days a week. For years I was told I had an irregular heartbeat but no side effects. I bought a watch that showed I had afib so I asked my Cardiologist about my concern, no side effects. I agreed to take medications to control the afib and Eliquis was one of them. My legs became so weak I have trouble walking over a mile and I am so tired I don't even work out anymore. Have appointment with my Cardiologist in 2 weeks, I hope I'm coming off Eliquis.