← Return to Forteo (teriparatide) followed by HRT: My Experience

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@tillymack yes; from what I’ve read Reclast is the go-to drug for managing Prolia rebound, though in some cases oral bisphosphonates like Fosamax can be considered based on a patient’s risk profile. Risk is influenced by many factors, including number of shots received, fracture history, overall fracture risk, bone density at stopping, and other individual considerations. In very high-risk patients, endocrinologists may monitor CTX to help guide the timing or frequency of Reclast infusions.

There’s a small study of 2 Prolia shots followed by Evenity, focused on BMD improvement but not powered to show rebound prevention.

Professor Langdahl has an excellent YouTube talk on managing Prolia discontinuation for anyone interested.

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Replies to "@tillymack yes; from what I’ve read Reclast is the go-to drug for managing Prolia rebound, though..."

@mayblin Thanks so much for your reply. I've been on Reclast for 3 or 4 years and have developed a small lump above my knee. My PCP ordered an MRI and the radiologist asked to have contrast added. Fortunately it was not found to be bone cancer but I wondered later if there could be a connection.

@mayblin

Thank you. This is timely for me. I had Evenity for a year with great results. I have had two prolia shots and now wondering if I could return to evenity i stead of having a lighter dose of reclast followed by evenity again. I
also began bhrt one year ago and hope that this will help support a transition from prolia.