Does anyone else have MGUS?

@mphaddican Why request am IGM score?And what is it it?

@mikxtr lab results for MGUS, Smoldering Multiple Myeloma or Multiple Myeloma can be complex and you really need to get your physician to explain, but I found this information helpful.
MGUS is a precursor blood disorder to Multiple Myeloma. It’s important to remember, however, that not all MGUS patients will get Multiple Myeloma. Many of us will live long lives without ever progressing. Some of our members have had MGUS for decades. The chance of progression is very low. It’s important to keep things in perspective.
Final point is made by my hem/onc doc all the time. Anxiety is not my friend. I should remember that in the unlikely event my MGUS does progress to multiple myeloma, it is treatable. Medical research has made significant gains. Huzzah! Hope this helps.

RE: Lab results

Understanding Your Lab Results
Multiple myeloma is a cancer of the blood—and the results of blood and other lab tests are important for diagnosing and monitoring multiple myeloma.

Your doctor or nurse will need to test your blood or urine on a regular schedule to see exactly how multiple myeloma affects you. These lab tests will help tell your doctor or nurse if your multiple myeloma is under control.
Below is a list of lab tests that are commonly used to keep an eye on multiple myeloma. Use the chart to help you better understand your results. Many of these terms and tests may be unfamiliar—you can read more about them in the glossary.
As you review these charts, please remember that “normal” ranges may vary slightly from lab to lab. Always rely on your doctor for a full explanation of what your results may mean.
LABORATORY ASSESSMENT
Serum Protein Electrophoresis

Protein
Normal rangea
6-8 g/dL
Albumin
3.3-5.7 g/dL
α1-Globulin
0.1-0.4 g/dL
α2-Globulin
0.3-0.9 g/dL
β-Globulin
0.7-1.5 g/dL
γ-Globulin
0.5-1.4 g/dL
Immunoglobulin, Serum

IgA
Normal rangea
61-356 mg/dL
IgG
76 7- 15 90 mg/dL
IgM
37-286 mg/dL
Chemistry Profile
Blood urea nitrogen (BUN)
Normal rangea7-20 mg/dL
Creatinine
Normal rangea0.6-1.3 mg/dL
Calcium
Normal rangea9-10.5 mg/dL
Creatinine clearance
Normal rangea
Males: 97-137 mL/min
Females: 88-128 mL/min
Glucose, fasting
Normal rangea70-100 mg/dL
Lactate dehydrogenase (LDH)
Normal rangea105-333 IU/L
Estimated glomerular filtration rate (eGFR)
Normal rangea
90-120 mL/min/1.73 m2
Serum-Free Light Chains
Free kappa
Normal rangea3.3-19.4 mg/dL
Free lambda
Normal rangea5.71-26.3 mg/dL
Kappa/lambda ratio
Normal rangea0.26-1.65
β2 -Microglobulin (B2M)
Normal rangea0.70-1.80 mg/dL
Complete Blood Count (CBC) With Differential
White blood cell count (WBC)
Normal rangea3.5-10.5 x 109/L
Red blood cell count (RBC)
Normal rangea
Males: 4.32-5.72 x 1012/L
Females: 3.90-5.03 x 1012/L
Hemoglobin (Hgb)
Normal rangea
Males: 13.5-17.5 g/dL (135-175 g/L)
Females: 12.0-15.5 g/dL (120-155 g/L)
Hematocrit (HCT)
Normal rangea
Males: 38.8%-50.0%
Females: 34.9%-44.5%
Mean corpuscular volume (MCV)
Normal rangea79.0-101.0 fL
Mean corpuscular hemoglobin (MCH)
Normal rangea25.0-35.0 pg
Mean corpuscular hemoglobin concentration (MCHC)
Normal rangea31.0-37.0 g/dL
Red blood cell distribution width (RDW)
Normal rangea11.0%-16.0%
Platelets
Normal rangea150-450 x 109/L
Lymphocytes
Normal rangea24%-44%
Monocytes
Normal rangea1.0%-10.0%
Absolute neutrophil count (ANC)
Normal rangea1.7-7.0 x 109/L
Urine protein electrophoresis
Protein
< 167 mg/24 hours
Albumin
< 5 mg/dL
α1-Globulin
0%
α2-Globulin
0%
β-Globulin
0%
γ-Globulin
0%
aLab values are ranges based on individual labs; values may vary slightly from lab to lab.
Always discuss your test results with your healthcare team and make sure to ask questions to fully understand what they mean.

Does this help? Hugs.

Sorry to be so vague. I am not a physician but my husband was diagnosed with MGUS many years ago. He finally made an appointment Dana Farber. His blood test showed an IGM high level and it indicted that he had Walldenstroms. It is very rare .
If the IGM is high it can indicate that. Don’t be afraid I am just throwing that out there. It is rare and some times missed
On a good note he has had infusion treatments over 6 years ago and is doing fine. His level has been normal.
Mayo is very familiar with that disease and has been helpful too.
M

@ems2012

Thanks for your response.

Since my husband’s treatments through Dana Farber his IGM levels have been normal for the last 6 years. They did find out that 40% of those with WM have a gene that normal treatment does not work for so they adjusted the infusions with that in consideration for my husband. It worked.
My high praises for medical research and researchers! They have to function in these uncertain times and they seem laser focused! Thanks to all of them! 😀