I just took my first dose of Repatha on Sunday. I woke up Monday morning with diarrhea, but as someone with severe constipation I was actually thrilled, I figured it was from eating one of my trigger foods, didn’t connect it to the drug. I took a fall in May and have had back pain on and off since then, so when by back began hurting yesterday, again, I didn’t attribute to Repatha. Thank you for pointing out that this drug could be the culprit.