They are both branded versions of an approach called subvastus or SubV. It involves going under the muscle rather than cutting the muscle and tendon. One thing causes me to somewhat mistrust the two approaches: there are many aspects of a total knee replacement including the method of alignment, whether one uses a tourniquet or tranexamic acid instead, the robot used, the implant used, and, MOST IMPORTANTLY, the skill and experience of the surgeon doing that particular technique. Neither one says anything about the process other than that it is subvastus.

I have a friend scheduled to have a TKR with a Jiffy knee surgeon. Mine is not but has been doing minimally invasive subvastus TKRs for more than ten years and even has a video on the web showing him doing a subvastus TKR in 2020 at an orthopedic convention. Mine also prescribed me tranexamic acid so that he doesn't have to use a tourniquet. My brother has a conservative older surgeon who used a tourniquet and he had severe pain because of it for at least a week.

I was chatting with my surgeon (he had some time because he had torn his rotator cuff skateboarding and was recovering from rotator cuff surgery) and mentioned my friend's upcoming surgery with a Jiffy knee surgeon. My guy said that the key issue in Jiffy knees was the skill and experience of the surgeon. He asked me who my friend was using. I told him (Timothy Kavanaugh) and he said that he is a good surgeon. So the key is finding the good surgeon.

The CT guided "customization" sounds like the company is using the Mako robotic system with the Conformis implant. Look up the Mako/Conformis system on the web and you will see. That is, by the way, a fine system. My guy uses the CORI system with the Journey II implant. Another excellent robotic choice.

I am hoping that my guy can do a bicruciate retaining implant. There is a Journey II variant that does that and my guy has considerable experience doing that. I don't know if Jiffy Knee doctors, or Nano Knee doctors, can or do implant bicruciate retaining units or have sufficient experience doing it. The surgery for doing a bicruciate retaining implant is more complex so having a very skilled and very experienced surgeon is important.

The best advice I can give anyone is find some one who uses the best technique and has considerable successful experience doing it. That could include Nano knee, Jiffy Knee, or anyone doing SubV knees (there are many). You should not have a problem finding someone in southern California who meets both criteria. One trick for finding a good surgeon is to see if she also does revisions. Revision surgery is complex and if the choice does a lot of them, she is probably pretty good.

Bottom line: my surgeon says that the most important requirement is having considerable successful experience performing the exact surgery that is proposed. I completely agree. If that means using a lesser technique (should not be an issue in Southern California), use the lesser technique. Experience is king.