Hi Jeff, I just looked at Rochard Wasserburgs utube session on estradiol. It sounds interesting , but I am scheduled for orchiectomy this Wednesday September 24th. Estradiol patch really sounds like it has complicated dosing. To much can cause blood clots and other issues. It may be something to look into if hot flashes and other side affects ate bad.I am really just wondering about your experiences with orchiectomy.