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Gabapentin - being linked to increased risk of dementia
According to a large scale observational study published in the journal "Regional Anesthesia & Pain Medicine", patients who received frequent gabapentin prescriptions were significantly more likely to develop dementia and/or mild cognitive impairment (MCI).
Researchers analyzed anonymized medical records from tens of thousands of Americans sourced from TriNetX, a federated health research network with electronic health records from 68 healthcare organizations across the country.
They found that patients whom had received six or more gabapentin prescriptions were 29% more likely to be diagnosed with dementia and 85% more likely to be diagnosed with MCI within 10 years of their initial pain diagnosis.
There is more - To view the full report:
https://doi.org/10.1136/rapm-2025-106577
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Hoch, what kind of shoes did you find? That were finally helpful. I have spent so much money on shoes. I can’t believe it. Right now I’m wearing go walk sketchers even the wide is not wide enough. Can you help me?
Bcool123
Be very careful with this product! Excess B6 is known to be a cause of neuropathy for some people. Do some research on B6 and neuropathy.
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2 ReactionsRight now, my favorite shoes are my Flux Adapt Trail Runner. I've been wearing them most of the summer. They have a wide toe box, which is most important to me. Occasionally, I'll wear some Lem's Chillum shoes that I have. They also have a wide toe box but less cushioning. Still, I like them. Last winter, I either wore my Flux shoes or a pair of Lems Boulder Summit boots. I have a lot of shoes right now that I cannot wear for one reason or another. It sucks. Socks also seem to be a problem. I can't wear them if they are too tight.
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2 ReactionsThank you for your response and I’ll look up your recommendation for shoes. I appreciate your help…bcool123
Same here! Summer was good that way -just sandals - no need for any shoe!
Drugs like gamapentin, duloxadene, (spellings?) etc. that mess with your nervous system are bound to lead to
some problems with your brain. Anything that gives you vertigo is bad for you
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1 ReactionI have been on gabapentin 800 twice a day for more than fifteen years. It wasn’t for pain but more as a mood stabilizer. The study is very vague and only included people with chronic low back pain. Does it matter why you started taking it? I need more details about this study instead of this is who we chose and this is what happened.
I take it for nerve damage
I was taking 2400 mg gabapentin per day for neuropathy.
The horrendous side effects were not worth the pain it helped resolve.
I am now taking 600 per day (before sleep) and have a medical marijuana license instead.
I also take high dosages of Lyrica & Cymbalta.
@harleysmom I take 900mg 3x a day for neuropathy in my left foot and leg caused by narrowing of my spinal canal from multiple fractures to my vertebrae or possibly elevated blood sugar for the past 35 years although A1c is usually 5.7-6.2. It makes me tired so I sometimes take a nap in the afternoon. I had a bad fall last year and hit my head hard. Tripped by another tourist in a very busy area. A few months later I had vertigo and loss of balance. Vertigo went away with therapy but still have balance issues. I have been noticing slight memory issues also. Jow do you determine if these symptoms are caused by aging or the gabapentin?