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DiscussionMy wife tested positive for jak2 and has high platelet count
Blood Cancers & Disorders | Last Active: Oct 3, 2025 | Replies (32)Comment receiving replies
Replies to "She is young. Most of us are diagnosed later in life. I was diagnosed at 69..."
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You didn't indicate how high her platelet count was. Mine started at 1.4 million and in 2 months was brought down to 480k (our goal) with 5 days a week of 1,000 mg Hydroxy and 2 days of 500.
In my case, the Hydroxy also lowered by white and red blood cell counts so it was a juggling act to balance the dose.
I, also, am shocked at the doctor's response to high platelet count. My diabetes endocrinologist saw high platelet initially, and thought her readings were faulty. She retested and it was worse. She immediately referred me to an oncologist ay Virginia Cancer Institute.
I was diagnosed with Profibrotic Myelofibrosis and high risk (previous colon cancer, aortic valve replacement and diabetes). I have 4 mutated genes (including Jak2). I took the BMB results to the cancer center at University of Virginia and they confirmed the diagnosis.
Part of my problem is that my cancer is rare (1 in 100k) and has only been recognized since 2016. Hope this helps.