My TRIMIX experience

Posted by maverick75 @maverick75, Jan 4 9:27am

I've been using Trimix for about six months with outstanding results. It did take some experimentation to figure out the best way to make it work for me. With hopes that it may help others, here's what I discovered using this medication: (BTW, I'm 71, one year post SBRT and 4 months Orgovyx)
- I have had to use the oral antidote several times (works well) in the early dose experimentation days for super hard erections lasting more than three hours (4tablets of 30 mg pseudoephedrine. Don't make the mistake of buying the extended release pseudoephedrine tabs). Make sure you have this on hand before you start this medication!
- I had to find the sweet spot for the injection site and depth. For me turns out to be the 10 and 2 o'clock position with the 1/2" needle almost fully inserted around mid-shaft.
- Shelf life on the Trimix in the refrigerator is limited. I can definitely see a difference in the results at the 3-4 week period. For me, it became pretty useless after 4 weeks, even at a higher dose. To help extend the life, I now fill all syringes with the needed dose as soon as I get the medication and immediately place all syringes into the freezer until needed. Now, I take a syringe out about 30 min before needed and it's ready to go. This is working well and my pharmacist said this should extend the shelf-life to 6 months or more.
- After injecting, massage the entire penis and base to help distribute the medication throughout the muscle structure. This will help significantly.
- Stand for the first 5-10 minutes after injection as gravity aids in the blood flow into the penis.
This medication has been a lifesaver for me. I was afraid I'd never see a useful erection again. Now, I'm back to 18 in that regard-- actually better than 18 as my erection stays hard even after an orgasm! Best of luck guys! Be aware that your partner may hide your medication if you use it to often. (-:

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

Best way to store Trimix, pre fill each of your syringes to the dose that works for you, get a dark colored tupperware, storage container and store each syringe in the freezer. When you need to administer a dose, take one out, rub the syringe with your fingers to thaw and now you have a storage window of up to 6 months instead of the 30 day timeframe.

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I like the freezing suggestion but not till you decide on the right dose , lucky you with ability of getting an orgasm , did you have radiation no surgery, I’m a year post surgery and feel nothing never mind getting an orgasm, I’m jealous

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What dosage did you find most effective? In units?

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Profile picture for jgrisham @jgrisham

What dosage did you find most effective? In units?

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The problem here is that everybody is different as everything else in prostate cancer. Usually, you work with your urologist to figure out what works for you.

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Hi Maverick,
I have an appointment with my doctor in a couple of weeks to discuss Trimix, and I’m a little nervous about it. Can you give me an idea of what to expect at my first office visit? From what I’ve read, it sounds like you have to test it right there in the office. Is that true, or can they let you take it home and try it out with your wife’s help?

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Profile picture for tj1967 @tj1967

Hi Maverick,
I have an appointment with my doctor in a couple of weeks to discuss Trimix, and I’m a little nervous about it. Can you give me an idea of what to expect at my first office visit? From what I’ve read, it sounds like you have to test it right there in the office. Is that true, or can they let you take it home and try it out with your wife’s help?

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I heard they definitely try it in the office and in some cases they have had people bring their wife so they have some Assistance with getting an erection.

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Profile picture for tj1967 @tj1967

Hi Maverick,
I have an appointment with my doctor in a couple of weeks to discuss Trimix, and I’m a little nervous about it. Can you give me an idea of what to expect at my first office visit? From what I’ve read, it sounds like you have to test it right there in the office. Is that true, or can they let you take it home and try it out with your wife’s help?

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They required I be ‘trained’ to use it in office. I do think it is necessary to learn correct procedure and needle placement. I had my ‘training’ in office with a PA. She instructed me and walked me through the procedure. I had to actually do the procedure and give myself the first shot right there in front of her. I measured the suggested dosage they use for first shots in the training . It turned out to be too big of dosage for me. It worked quickly, but I ended up going to ER that evening after 4+hrs. By the time they saw me (another 2 hrs later) things had started to recede and I didn’t need any treatment. Kind of scary though. I cut way back and eventually found the dose for me.

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Question for you. I see you're one year post SBRT and Orgovyx. I am too. Did your testosterone never return? I'm 62 and was told that I'd likely see a fairly rapid recovery after Orgovyx but that hasn't been the case at all. Fortunately, Viagra is still working for me but who knows for how long.

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Profile picture for jeff Marchi @jeffmarc

I heard they definitely try it in the office and in some cases they have had people bring their wife so they have some Assistance with getting an erection.

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That was correct for me!

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Profile picture for tj1967 @tj1967

Hi Maverick,
I have an appointment with my doctor in a couple of weeks to discuss Trimix, and I’m a little nervous about it. Can you give me an idea of what to expect at my first office visit? From what I’ve read, it sounds like you have to test it right there in the office. Is that true, or can they let you take it home and try it out with your wife’s help?

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I did not try it in the office. My urologist gave me instructions and faxed in a prescription for me to MenMD. I received a phone call and was given more instructions about how to handle the medication (refrigeration, etc.). My hands are a little shaky, so I invested in an auto-injector which made the process quite easy. There are numerous YouTube videos available from MenMD and other sources that walk you through the whole process.

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