The only treatment currently approved that sufferers say works best, and I'm not talking about any medication that might be known to help, is what is called an 'adaptive servo-ventilator' or ASV. It's the same beast that the hospitals use for COVID patients who are in a bad way and unconscious, not able to do much of their own breathing. I don't know what the professional machines cost, probably USD $4K or so, but the RESMED version are about $2K. That's two or three times what a regular CPAP machine costs. But the ASVs do a much better job at both detecting that a central event is happening, and then puffing down the hose and stimulating the unconscious patient to resume breathing. That's the mechanism. The machine monitors flow via a 'manometer' in the hose, and if it senses that there is an 'open airway' (no obstruction), then it knows to send several higher pressure pulses down the hose as a nudge. For the most part, most patients with diagnosed and otherwise poorly treated CSA, the ASV works well. Note that your insurer, if you need help from them, will want a formal diagnosis in all cases, and they may even resist purchasing an ASV until you have exhausted all other forms of PAP therapy, including Bi-PAP and AutoPAP.