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Brinsupri (aka Brensocatib)

MAC & Bronchiectasis | Last Active: 6 hours ago | Replies (161)

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Started Brinsupri yesterday 25mg once daily. I think an added bonus for me is that I had a CBC blood work done yesterday as well, which shows my neutrophil count in my blood, which has always been high since I’ve had BE. Now my Pulmonologist did not order any additional bloodwork in the coming months, but i will ask her that this week if I should be getting bloodwork done periodically. It seems like it would be logical to monitor the neutrophil count while on Brinsupri right? Was anyone in the clinical trials and had bloodwork done while on Brinsupri? If yes how often? I will be sure to let everyone know how it’s going for me as I take this new medication for us. Fingers crossed 🤞

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Replies to "Started Brinsupri yesterday 25mg once daily. I think an added bonus for me is that I..."

All the best to you! It would be interesting to see if your neutrophils go down. My understanding is that you would still have the same neutrophilic response, but it would be moderated and not over the top. So I don’t think the number of neutrophils would go down based on taking the drug, but who knows… also at the higher dose the Aspen study showed an improvement in FEV1.

Keep us in the loop and again fingers crossed, Linda Esposito

Wishing you the best on this new med! Are you on meds for NTM concurrently?