← Return to Waldenström macroglobulinemia (WM): Anyone on zanubrutinib (Brukinsa)?

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I'm 68 years young and diagnosed with Waldenstrom's Macroglobulinemia 8 months ago. My oncologists/hematologists started me on Brukinsa (Zanubrutinib) at the time of diagnosis. Same dose as murray3 (4 capsules of 80 mg) daily.
I tolerate Brukinsa very well and it's helped my IgM value significantly. While still very high it's half what is was before Brukinsa.
Before diagnosis, my symptoms of WM were fatigue, rapid heart rate when doing physical tasks, fainting (with little warning), anemia and peripheral neuropathy. While rapid heart rate and fainting have (thankfully) subsided I still have low-moderate anemia and neuropathy (fingers & toes mostly). I received IV Iron once per week for 4-weeks which helped with anemia - the neuropathy is manageable (I use handwarmers - and heating pad for my feet) which helps with pain, numbness, tingling and cold in my extremities.
My Medical Team (UCSF & Sutter) feels good about the effectiveness of Brukinsa and my body's response - indeed I'm trending in the right direction 🙂

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Replies to "I'm 68 years young and diagnosed with Waldenstrom's Macroglobulinemia 8 months ago. My oncologists/hematologists started me..."

I am glad to hear that Brukinsa (Zanubrutinib) appears to have your WM under control currently. With respect to your peripheral neuropathy (which I also had), you might like to locate a Doctor of Acupuncture from whom you can receive regular weekly manual and electro-acupuncture treatments. These treatments worked marvellously for me. The sooner you are able to set up regular weekly acupuncture sessions for yourself, the more effective the treatment will be.