I have CMT, which is a rare neuropathy and affects my entire body, that was diagnosed in 2022. The muscle spasms have been so severe that I can't move or walk and sore for several days. I am on magnesium and muscle relaxers. Staying hydrated is supposed to also help. Doctor suggested drinking a bottle of Pedialite every day. I use a powder form of electrolytes in water that helps. These spasms come on so suddenly, day and night, that I knew I needed something that would help immediately. What has been working for me when I feel one coming on is pickle juice. I carry it with me everywhere and have by my bed It truly has been a blessing. It doesn't interfere with the meds and stops the spasms before it goes to the "I can't take it anymore stage." I hope this helps you as it has me. Prayers for you all.