For me Ojjaara was a game changer. I went from hgb 7- to 12-13, and it has held for over a year. My major spleen issue went away. I've expanded on my case in several post so I won't go through all of that again. But the bottom line is that I'm 78 yrs, been fighting MF for MANY years. I was down to surviving on Transfusions and Ojjaara turned all of that around. I now have a more than normal life for a 78 yr old. I walk 2 mi every morning, attend a full exercise class three time a week, travel in my RV, and have resumed my competition action events at the World Games and other events around the Western US. My side effects are well worth it, and so far very manageable. IMO, Ojjaara is well worth trying. It has completely changed my life. Don't know how long it will last, but for now I'm enjoying life to the fullest.