Hello @brianjarvis, This news about your friend has to be devastating. I’m so sorry to hear that the prognosis isn’t encouraging. Leptomeningeal cancer is not in my area of experience but I was able to find several references in the forum with other members who have been similarly diagnosed.

Below is a link to the results of my search. Hopefully there are some relevant discussions for you.
https://connect.mayoclinic.org/search/
What has your friend’s doctor suggested to keep her comfortable. Is she in palliative care or possibly hospice?