Evenity and side effects: What helps joint and muscle pain?

I am wondering the same thing. It took two weeks for my pain to go away.

Has anyone read that there are indications that after six months of Evenity you reap 90% of the effectiveness of the medication?

How did the next shot go and what did you decide to do? I am having such stiffness and don’t know if I can keep this up if it doesn’t subside.

Hello @bruceandruth1970, I combined your discussion into another discussion on Evenity side effects and how members are managing joint and muscle pain:

"Evenity and side effects: What helps joint and muscle pain?"
- https://connect.mayoclinic.org/discussion/evenity-and-side-effects/

Here, you'll be able to read through how members handled their Evenity side-effects and how some members had their symptoms go away after a short period of time.

Just wanted to report that I had my fourth shot last Friday and am not experiencing any joint or muscle pain. My arms were sore for a couple of days but so far I have not had the same experience as previous shots with painful joints and muscles. I've read here that sometimes the joint and muscle pain dissipate as treatment continues so I am hoping that's what is going on in my case.

Hello everyone! I had my second dose of Evenity last week and I have severe joint pain in my left hip lower back and thigh. I'm on day 4 of this and taking Motrin every day. Doctor said it shouldn't last longer that 5 days but I'm not holding my breath! Anyone else have this happen? What did you do? I hate to stop the evenity! Help!!!

My experience has been wildly variable after each injection. First injection I did not have much joint or muscle pain. Second shot I had pain that started a few days after and lasted about a week. Third shot the pain started immediately and lasted two weeks. I had my fourth shot last Friday and initially had very little joint or muscle pain (and even posted that yesterday). Unfortunately, five days after my shot my right hip and knee started hurting, enough to wake me last night.

I take two extended release Tylenol every night at bedtime. This lasts about six hours but then I am awakened by pain.

So, my experience is that it seems to be different every time. I am sticking with the medication, though, in the hopes of it helping me build bone. The pain and disability I had following my compression fracture was much worse and if Evenity helps me avoid another fracture then I am willing to put up with the discomfort.

I have been suffering with terrible joint pain in my knees and now I have tendonitis in the back of my knees. I lost all muscle mass too. I have 5 more treatments.
The injections are so painful and my body swells around the injection site for over 7 days each time.

Are they insuring that the Evenity is not cold before injection? It is much easier when it is not too cold

I will find out on Monday when I go back. My endocrinologist said that I can have both injections in the one arm since I had lymph nodes removed on my left side.