Actually, it depends on the person. HU made me lose hair and vomit. My hair was coming out in clumps. After I started taking Essential Amino Acids (Doublewood brand), my hair stopped falling out and grew back in, albeit a little fuzzy now. HU also affects my digestion, including nausea and vomiting. I take some supplements and herbs to help counteract that side effect. Here’s the reason why. Chemo targets rapidly dividing cells, which is why HU works so well for ET. My high blood count stays under control with the med. But hair follicles and mucous membranes are also rapidly dividing cells, thus the hair loss for some people. Chemo degrades the mucosal barrier of the digestive system, given that it is made up of mucous membranes. Some people are not affected at all, but I am so I take a few things to help in that area, and I have to continually keep Candida albicans overgrowth in check. Mouth sores is another side effect of chemo, because of mucous membranes in the mouth. I was getting just one at a time, then I read on here the recommendation to use a zinc mouth wash. I opted for zinc lozenges which I suck on once or twice per day, and no more mouth sores. It’s so different for everyone, and I hope for the best for you on your journey.