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Evenity injection site pain

Posted by neesie0159 @neesie0159, Oct 8, 2023

Last week I had my 3rd Evenity injections. The MA told me with the first ones that they don’t cause sore arms because they’re given subcutaneous instead of IM. I had them in the morning, by evening my arms were very painful and that lasted into the next day. When I called the rheumatology office for advice I was told this never happens. Right. Same experience the second shots, though slightly less pain. Last week I had a different MA give the injections and mentioned the arm pain, she said that shouldn’t happen. Very minimal pain that time until late afternoon, then I was strapping ice packs to my arms.
Has anyone else had injection site pain?

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v1tality | @v1tality | Jun 30 8:36pm

The tender pain is severe beginning 3-4 hours following the injection and it continues for 2-3 days. I wish I could find a way to minimize this discomfort since this was my third injection today. I have had different nurse administrators each time. I typically alternate sites between arms and abdomen. I am glad you found some relief and I hope I can too. I wonder if there is a special protocol that should be followed for the injection. Your thoughts?

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coinholio | @coinholio | Aug 20 11:24pm

I had my 1st Event injections in my bat wings (flab hanging from the arms). 2.5 days later, not really too painful but a hard lump under the skin the size of a peach pit. Slowly going down. But will I spend up to 25% of my life with lumps? I will definitely try the abdomen next time.

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coinholio | @coinholio | Aug 20 11:27pm
In reply to @thesandpiper "Had my first Evenity shots yesterday. The left arm injection was not a problem. The right..." + (show)
Profile picture for thesandpiper @thesandpiper

Had my first Evenity shots yesterday. The left arm injection was not a problem. The right arm injection burned somewhat and was uncomfortable. Today my left arm site has just a little redness, about an inch in diameter. My right arm injection site is hot to the touch, has a lump in it, and has redness about 1.75 inches in diameter. Go figure.

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I had my 1st injections in my bat wings. Tender with lumps 2.5 day later.

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barbyb50 | @barbyb50 | Aug 21 11:11am

I have getting the shots in my abdomen. Just some tenderness but no other problems. One time had bruising. I’m sticking with that site based on other comments. Was told that there isn’t any down side to always have the same site.
4 down and 8 to go!

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lbarbato18 | @lbarbato18 | Oct 4 8:58am

I SOLVED THE PAIN at my stomach injection site. After my first shots, I had no pain on the left side, but uncomfortable pain for 10 days on the right. I noticed the shots were administered in different locations. The left injection was 3 inches left and 1 inch down from my naval. The right injection was 2 inches immediately to the right. For my second set of shots, I brought a sewing measuring tape and had the nurse inject both sides at 3" away and 1" down from my naval. No pain! For me, I think having the shot in a fattier area farther from the naval really made a difference for me.

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gravity3 | @gravity3 | Oct 4 9:08am
In reply to @vrgarden "@neesie0159 This is from the Evenity website: "---------------------------DOSAGE AND ADMINISTRATION------------------- • Two separate subcutaneous injections are..." + (show)
Profile picture for vrgarden @vrgarden

@neesie0159
This is from the Evenity website:
"---------------------------DOSAGE AND ADMINISTRATION-------------------
• Two separate subcutaneous injections are needed to administer the total dose of 210 mg. Inject two syringes, one after the other. (2.1)
• Should be administered by a healthcare provider. (2.1)
• Administer 210 mg subcutaneously once every month for 12 doses in the
abdomen, thigh, or upper arm. (2.2)
• Adequately supplement calcium and vitamin D during treatment. (2.2)

and this is from the package Insert from Drugs.com:Prepare and clean two injection sites, one for each of the two injections. See Figure B.

Figure B
The recommended subcutaneous injection sites include:
● The thigh
● Abdomen, except for a two-inch area right around the navel
● Outer area of upper arm
Prepare and clean two injection sites, one for each of the two injections. See Figure B.

Figure B
The recommended subcutaneous injection sites include:
● The thigh
● Abdomen, except for a two-inch area right around the navel
● Outer area of upper arm

I tried to include a diagram from the Package Insert. But if you put Evenity in your search bar and scroll down to Drugs.com Evenity Injection: Package Insert-Drugs.com, then click on Dosage and Administration, scroll down to 2.3 Preparation and Administration Instructions and read and scroll you'll see the diagram.

I hope that helps.

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@vrgarden

This should be given to every patient prior to commencing treatment

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clj9821 | @clj9821 | Nov 17 8:02pm

I had #10 today.. Yay for me. I started with injections under my arms for a few, then stomach for 2 ish and since then my thighs. Every pace has led to big red welts that feel warm and burn. I use ice packs.. and because I’m on Eliquis I can’t take my tried and true Advil so I have to be satisfied with Tylenol and it doesn’t do much for me. I feel that some discomfort is to be expected and it has to be a thing because so many ask about it. Hang in there.. time goes quickly. I’m praying that it’s worth it. I will have 3 years of Reclast unless the plan changes per my Endocrinologist in Denver. I am a Mayo Clinic MN patient also and my Endocrinologist there, Dr Clark agrees 100% with my plan. It’s hard some day and worth it most. Take care, Cynthia 🙏💕

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