What’s the science on diet and MGUS/SMM?

Posted by Patty, Volunteer Mentor @pmm, Sep 19, 2022

Is there any evidence that progression of MGUS or SMM is slowed by dietary changes? Avoidance of types of food? Addition of specific spices to the diet?

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Profile picture for jackir @jackir

I was just diagnosed with Waldenstrom’s and my first appointment at Mayo in Phoenix is the second week in November. I live in the Phoenix area, originally from Sioux Falls, South Dakota and went to University of Minnesota so I am more familiar with Mayo in Rochester. Should I try to get an appointment in Rochester? I have always heard the only place to go is Rochester. I would appreciate any feedback.

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I am not knowledgeable about Waldenstrom’s but I live in Dayton MN and have SMM Smoldering Myeloma. Diagnosed a couple weeks ago. I am being seen at Virginia Piper Cancer Center at Abbott Hospital in Minneapolis. I am getting a second opinion at Mayo in Rochester as to the watch and wait or possibly get into a trial study. The Mayo has a lot of trial studies. I suggest at least looking at the trials and speaking to them. Never hurts.

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Profile picture for ChefT @cheft

I am not knowledgeable about Waldenstrom’s but I live in Dayton MN and have SMM Smoldering Myeloma. Diagnosed a couple weeks ago. I am being seen at Virginia Piper Cancer Center at Abbott Hospital in Minneapolis. I am getting a second opinion at Mayo in Rochester as to the watch and wait or possibly get into a trial study. The Mayo has a lot of trial studies. I suggest at least looking at the trials and speaking to them. Never hurts.

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I did exactly that. Started my chemo last Thursday. No bone lesions so far, but high-risk active myeloma based on DNA and blood tests. Very fatigued, but very optimistic. Two days after starting chemo no noticeable side effects. No nausea. So far so good.

I moved to AZ to be closer to Mayo. It was either Rochester or Phoenix and I have an orange tree here and no snow.

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I hope with you for a good outcome. Let us know how this goes for you. It sounds like the chemo is manageable. That’s excellent.
Patty

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Profile picture for lovelydavina @lovelydavina

I'm not sure if there is any evidence on any specific diet related to
Monoclonal gammopathy of undetermined significance (MGUS), which is what I have.
However I have been a vegan for 20 years and about the time I was diagnosed with magus, (approx 8 years ago), I had been eating a very lot of pure peanut butter on a regular basis. Then I read peanuts are actually very bad for you and can even increase proteins in your blood. I since stopped and now only moderately eat almond butter. My doctor said she really didn't think it was related. My yearly blood tests now are always with low enough levels, but the protein is still present, but still posing no threat. I really don't have any other major issues aside from my normal allergies, my weight is low and I'm healthy. I feel that being a vegan, eating lots of green asian vegetables, mushrooms, non gluten breads and rice, (I have Celiac), and drinking teas is the way to stay healthy and to live a long life. Hopefully that will continue to be the case.

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This is the first I’ve heard about pure peanut butter being unhealthy and possibly increasing protein in blood. Do you have a reference for that statement? I eat peanut butter regularly and almond butter too.

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Profile picture for bobbyd1017 @becky1024

Since I have so many things wrong with my body, some rare, some very rare, I do a lot of research on this subject. So I can verify the answer to your question and it is yes but complicated. Since I have two very serious problems with my blood and heart, plus my kidneys, immune system, peripheral neuropathy and brain, I researched using this simple question. Is this good or bad for my (specify condition) including cancer and my Kappa light chain IgM MGUS that’s slowly progressing to either MM, NHL or WM. Example: Is potassium good or bad for my Stage 3 CKD. Answer: Bad

When I focused on my MGUS, I asked are tomatoes good or bad for my MGUS progressing to cancer? The answer was Bad. Why I asked? It seems certain cancers cells love an acidic blood level and cause them to multiple easier. Then came this answer, an acidic blood level can repress breast cancer cells from multiplying rapidly. This answer was noted from a survey on the topic. I’m unsure of what cancer it mentioned but I believe it was breast cancer and it was reported from a study and not a definite fact. So yes, according to that question and answer, certain things can be good or bad depending on the type of cancer. I asked about foods, drinks, vitamins, vegetables, fruits. On the topic of one food, it was good for one condition but bad for another condition. So I chose to eat it since it helped my one condition that was more dangerous to me and I’m paying the price from the other condition. So I hope this answers your question. But remember this, how much help or damage something will do to your body is subjective at best. @becky1024

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@becky1024 There's a problem often with info gathered online. The body maintains homeostasis through kidneys, breathing (lung exchange ofO2 and Co2), sweating. pH scale i centers around neutral = 7. Water is 7. Blood normal range is 7.35 to 7.45.slightly alkaline. Because above 7 is alkaline "BASIC" and below it is ACIDIC. A change in blood pH is a big deal and when the body is in alkalosis or acidosis, you'd be pretty sick. There's a list of diseases that can impact pH of blood.

I can't post links so look this up: Healthline, "What’s a Normal Blood pH and What Makes It Change?"

So, Can eating food change the pH of blood? Stomach is acidic 1.1-1.3. First remember that stomach acid [Hydrocholic acid] creates an acidic environment for digestion of proteins. so food goes through changes through these digestive exposures. The pH of a food when it goes in is immediately changed. So eating an acidic food like tomatoes, citrus does not influence the blood.
read this: biology insights "Can food throw off your ph-balance?"
Homeostasis maintains all our systems within certain parameters to keep us alive.
So the food thing is basically (haha) bogus.

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