Evenity worked for me: Why I chose medication for osteoporosis

Posted by monkhhi @monkhhi, Dec 1, 2024

I just completed a year of Evenity and had my f/u Dexa. My first Dexa was in 2015 when I was in my 50s. My OB/GYN suggested it as I had broken a bone in my 40s. That Dexa showed osteopenia in my lumbar spine with a score of -2.4. At that point, I was adamant that I would not take any medication. I increased my calcium and kept up my running and weightlifting. I also decided that since I wasn’t going to take any meds, I wouldn’t bother with f/u Dexas. I started seeing a new NP who convinced me that I should see what my scores were in 2023. I was shocked to see that my lumbar spine was now-3.4. That was a real wake up call! Severe osteoporosis.

So I was still set on not taking medication, especially after reading a lot of the discussions on this site. I spent most of 2023 running more, lifting heavier, yoga, Algae Cal and Strontium (yes I know Strontium shows false strengthening). I hiked in NC that summer with a heavy backpack. But in the meantime, I read all of the books recommended, researched the medications, and made an apt with the osteoporosis center at our large teaching hospital. My plan was to see if I could improve my results naturally. I would pay for another Dexa out of pocket to see if anything changed.

In Oct I went to see the provider that runs a large osteoporosis clinic. I told her my plan. She was very honest with me. She said I would be wasting my time and money. She felt that my osteoporosis was genetic. I was already doing everything I could including bio identical hormones and my score was worse. She said to stop the Strontium which I did. She said that osteoporosis was a chronic condition. You can improve it with medication but once you stop, you will begin losing bone again and go back down. I would have to be on something for the rest of my life. I elected to start with Evenity. My labs were good and remained good. I had no side effects from the medication. I chose Evenity due to my Medicare coverage. I have Medicare A/B, plus a D plan and a gap plan. Tymlos and Forteo had large monthly deductibles. Evenity was covered at 100% because I went to an infusion center and it was covered under Part B and my gap plan. Also Evenity targets the lumbar spine and that was my biggest problem. Even though I had a lot of hesitation, I decided to trust my provider who follows a large patient population of osteoporosis. I was concerned about side effects but I pulled up the actual clinical trials and read them. The # of severe side effects were actually very low and were almost equal in the placebo and medication group. My provider confirmed that and said that my chances of a severe side effect would be very low but my risk of a fx was very high and that would change my life. She said that the serious side effects were not showing up in the general population of people taking the medication.

My latest Dexa showed improvement in my lumbar spine to -1.8 (from -3.4). I will switch to Prolia next month. I would encourage anyone hesitant to start medication to read as much as you can and discuss with your provider. I also chatted with the infusion center nurses and other patients that I met at the center about Evenity and Prolia to see what their experiences were. Everyone said the same thing, that most patients do very well. Occasionally, someone needs to change their medication but that was rare. Also, I’m pretty healthy. There are some patients with multiple comorbidities and they might have more issues.

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

Just wanted to tell people that I had my first Evenity shots last Weds. and had no side effects, which the doctor indicated would probably happen very soon if they were going to happen (bone and joint pain).
So relieved!
But I guess we'll see. 11 more months to go.

REPLY

I was so nervous for my first shots, but I asked the nurses how patients usually do and they all said fine. I took Evenity for the full 12 months and had no issues at all. Good luck!

REPLY
Profile picture for pami @pami

That is wonderful your body responded so well to the Evenity. I hope you get more gains on the Prolia. I will probably go on Prolia after Evenity. Let me know if you continue to improve.

Jump to this post

Pami,
Have had my second injection of Prolia and will have another DEXA in August. I have had no side effects so far. The only thing was that my calcium dip was on the low side and I had to increase my intake and now it’s all good.

REPLY
Profile picture for pami @pami

That is wonderful your body responded so well to the Evenity. I hope you get more gains on the Prolia. I will probably go on Prolia after Evenity. Let me know if you continue to improve.

Jump to this post

Wanted to let you know that after being on one year of Prolia just had my DEXA and was so disappointed. After Evenity it was -3.3 and now with the 2 injections of Prolia it is -3.2!

REPLY

I had great gains with Evenity then went on Prolia which has been a year and my DEXA shows no gains. I talk with my endocrinologist Friday and am going to see if I can go back on Evenity. If anyone reads this and has done more than a year of Evenity please share.

REPLY
Profile picture for kristie2 @kristie2

Pami,
Have had my second injection of Prolia and will have another DEXA in August. I have had no side effects so far. The only thing was that my calcium dip was on the low side and I had to increase my intake and now it’s all good.

Jump to this post

No gain on Prolia very disappointing. Talk to my endocrinologist on Friday we will see what’s next.

REPLY

I've had a similar experience. Just began Evenity and no side effects. I'm from Eastern European descent fair hair and skin and slight of frame. I believe it's genetic. I still work out, do yoga, take calcium, don't drink or smoke.

REPLY

I have been on Evenity (after a few years of Prolia) since January. Had my 7th shot last month and so far, so good. I don't think that there are side effects, although I do wonder about internal organs, etc. But there's nothing obvious to me and the only pain was at the injection sites. I have mastered this by taking Tylenol right before or after the injections.
I will have another DEXA in January and report back on whether I made any progress.

REPLY
Profile picture for kristie2 @kristie2

I had great gains with Evenity then went on Prolia which has been a year and my DEXA shows no gains. I talk with my endocrinologist Friday and am going to see if I can go back on Evenity. If anyone reads this and has done more than a year of Evenity please share.

Jump to this post

I have read the research on Evenity, and there is no gain after a year. As in; It does all it can do within a year. I was actually wondering if you RESTART after "X" amount of time if you can potentially get another "boost" out of it! But I have not found any evidence that this has been tried or documented.
Personally I think you might try some other options. Or at least ask about other options.

REPLY
Profile picture for pauladiamante @pauladiamante

I have read the research on Evenity, and there is no gain after a year. As in; It does all it can do within a year. I was actually wondering if you RESTART after "X" amount of time if you can potentially get another "boost" out of it! But I have not found any evidence that this has been tried or documented.
Personally I think you might try some other options. Or at least ask about other options.

Jump to this post

Have you seen this report?

Shared files

Evenity-24 months (Evenity-24-months.pdf)

REPLY
Please sign in or register to post a reply.