← Return to Reason for GFR level to fluctuate from 20 to 57?

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Profile picture for Ginger, Volunteer Mentor @gingerw

@roz27 Welcome to Mayo Clinic Connect.

Yes, it is possible to have your eGFR rebound back to more acceptable levels. But it takes a lot of work on your part, to be honest. You say your high blood pressure is more managed. It is not an instant reversal, and sometimes if the damage was done it may not be able to recover.

Good solid exercise, following a sound renal diet, taking the appropriate medications that your medical team suggests will help a lot. What is a good renal diet? Limiting salt, processed meats, phosphorous, potassium, calcium, NSAIDS [like Alleve], watching your protein intake. There are several helpful renal guidelines:
from the National Kidney Foundation: https://www.kidney.org/nutrition
from DaVita Kidney Care: https://davita.com/diet-nutrition/
Ginger

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Replies to "@roz27 Welcome to Mayo Clinic Connect. Yes, it is possible to have your eGFR rebound back..."

My creatinine (a protein used to measure GFR) and eGFR levels were normal range for years, until I got norovirus in December, 2023 while I still had long covid. My eGFR went from 77 in Sept. to 35 in Jan., likely due to rapid onset severe dehydration, high temperature, and inflammation. Covid did result in spikes in high blood pressure, but my resting BP is normal range and no risk factors for kidney disease other than being 70 (active, normal weight, already on a renal diet because of hubby, etc). Going on 2 years later my eGFR ranges from 32 to 45 and my kidney biopsy in June showed moderate scarring of my renal tubes and glomera (filtering cells). I didn't tolerate Lisinopril so one month ago I started 10 mg/day Jardiance, a pricey SLGT2 inhibitor. So far it has changed my average BP from 119/69 to 108/73 (systolic is more important than diastolic for heart/kidney health). So far no change in creatinine levels (which are what eGFR reflects), but that can take several months according to the doctor. Other than some fatigue, I don't have AKI or CKD symptoms. SLGT2 inhibitors don't seem to cause symptoms in me. Diet, avoiding stress, and getting enough aerobic and resistance exercise is important.