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Bra or gynecomastia surgery?

Prostate Cancer | Last Active: Aug 17, 2025 | Replies (10)

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Profile picture for Jeff Marchi @jeffmarc

I would really like to hear from people that are on the combination of drugs mentioned. Have other people had problems with gynecomastia taking this drug combo.

Lupron and Orgovyx should be equal in results.
Same with Erleada and Xtandi

Trying to figure out how common this is with just these drug combos.

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Replies to "I would really like to hear from people that are on the combination of drugs mentioned...."

I'm just coming up on 3 months in(Orgovyx / Nubeqa), Jeff and there is a noticeable difference. Now I don't know if it's actually gynecomastia, or just a loss of muscle mass appearing as such, but it's different for sure. Like I said, I just bought bigger shirts. I don't care which it is enough to have it scanned. I did increase upper body reps during work out to see if it will make a difference. This whole journey did start with kidney failure and my understanding is that could be a contributing factor.

Jeff, my apologies but take me of the list of ADT causing gynecomastia. I was just rereading my PSMA Pet scan report. Listed in additional findings is "mild symmetric gynecomastia". Since this test was done prior to beginning ADT, the drugs obviously didn't cause this, but more likely, the lowered testosterone level is enhancing a pre-existing condition, which is either age related or caused by my excursion into kidney failure. In either case, since it's not going to kill me, I'm still just buying bigger shirts. 😁