I sleep with a pillow under my legs and change its position thru the night to between my legs or under one leg. I am on pramipexole (sifrol) which I take 2 hours before bed, during the day the only thing that helps me is walking as long as I can around the house, I can't go out walking for long due to other health issues. My problems started when I was pregnant 52 years ago. There is no cure all unfortunately but what I am doing does help me to a degree, I still nearly go crazy with it at times!! It's trial and error to see what helps you. Good luck finding what helps you.