Connect
← Return to Have had 38 cycles with Abraxane & Gemczar. CA19-9 rising.
Discussion
Have had 38 cycles with Abraxane & Gemczar. CA19-9 rising.
Pancreatic Cancer | Last Active: Aug 16 7:06am | Replies (21)Comment receiving replies
Hi
First of all, you're a role model. I've now gone through 20 cycles and 41 treatments of the Abraxane & Gemczar combo over the past 20 months. Nice to hear that you and others have gone longer.
Same situation with the neuropathy (particularly in my feet) gradually increasing.
Couple ideas for you:
1) A new immunotherapy was recently approved for bladder cancer, Anktiva. It was invented by the same guy that invented Abraxane so the credentials are there. It's now been granted Expanded Access Authorization for pancreatic cancer. But you must be in a state of lymphopenia to qualify. Just had the conversation with my doc this week. I'm not there yet. If you are, it might be worth considering.
2) Daraxonrasib (RMC-6236) - don't know much about it but apparently in a Phase 3 study. https://clinicaltrials.gov/study/NCT06625320 Has potential but still might be out a year before approvals.
By the way, are you icing hands and feet while being infused with the Abraxane?
Best wishes.
Replies to "Hi First of all, you're a role model. I've now gone through 20 cycles and 41..."
I spoke with Dr. Seery yesterday about the trial requiring lymphopenia. The only result they were looking for was if the trial increased the lymphocytes- that's the only positive results they were receiving.
Connect
I found out about icing rather late during chemo (like over 6 months). I found acupuncture to be helpful, but now my acupuncturist says it is mainly to prevent increased neuropathy rather than prevent it. When I had a four month "break" from chemo I did find the neuropathy did decrease some 🙂
The RMC-6236 sounds tempting if I don't have to go to California 🙂
Thank you.