It binds to the opiate receptors in the brain, theoretically tricking the brain into producing more. It is used for people with opiate addiction and alcoholism, higher doses 25, 50, 100 mg and so on. I am using 25 mg as I have tried the low dose which has to be made specifically for lower doses as the pharmaceutical companies do not make lower doses than 50 mg. I hope that makes sense.

Naltrexone was originally used to treat both opioid and alcohol use disorders at a dose around 50 mg or more. For people at this high dose, it binds the opioid receptors and prevents them from feeling high if they use their drug of choice.

Lower doses, from .01 mg to 4.5 mg, has been found to help people with Long COVID, chronic fatigue/pain, fibromyalgia, Crohn’s and other dysfunctional immune system disorders. At this small dose, it blocks the opioid receptor for about 1.5 hours and then provides analgesic and anti-inflammatory benefits. When it unblocks the receptor, I get more energy from the increase in endorphins and it greatly decreases the inflammation that gives me so much pain. You would not benefit from this medication if you routinely have to take an opioid for pain relief as the opioid will not work properly.