← Return to Prefibrotic Myelofibrosis: Diagnosis Favors Essential Thrombocythemia

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Profile picture for nohrt4me (Jean) @nohrt4me

So glad that you got some answers!

Yes, ET-CALR is suspected to be a somewhat different "animal" than ET-JAK2. The big difference now is that it keeps many of us CALRs in the low to moderate risk groups, which means we don't need to start HU as soon.

Age alone is not a reason to write off BMT. It's not something I would consider given other health conditions and low income, but it has clearly helped many folks here get a second chance!

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Replies to "So glad that you got some answers! Yes, ET-CALR is suspected to be a somewhat different..."

Hi again @nohrt4me ,

I honestly don’t know if I would choose to do a bone marrow transplant even without having other health conditions because even with CALR mutation, the odds of being alive after five years is only estimated at 64%. Perhaps if the odds improve years from now, I might have a different opinion. MPNs to me are an evolving field with much still not known.