Years ago I took amlodipine and had major ankle and feet swelling. Tried it for months but had to stop. My dad had the same issue. I have been trying different bp meds for 20 years but never under control. Two years ago a PA at my cardiologist practice wanted me to add amlodipine to my olmesartan prescription. I told him my history and he said the problem was not the medication but the high dose. He asked me to start at 2.5 mg daily and if no improvement after 10 days increase to 5 mg daily but never higher than 5 mg. Within days of taking the 5mg dose, my blood pressure was perfect. I've stayed on daily 40 mg olmesartan with 5 mg amlodipine and never have high readings at home. Always high readings at doctor appts but I take my daily home reading history to put in my medical records. Took over 20 yrs to find the right combination of meds that finally worked for me. The PA finally solved my high blood pressure and anxiety after having no success with several primary care doctors and several cardiologists and many different prescriptions.