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Is there anything to help stop or slow progression of MGUS?
Blood Cancers & Disorders | Last Active: Oct 19 11:26pm | Replies (153)Comment receiving replies
Well I gave up on taking high doses of Curcumin and now am betting that lowering my BMI is my best bet. I've had IgM Lambda MGUS for about four years. The progression started slow but quickly picked up speed. Last November, I started using high doses of Curcumin and at the same time was using a CGM to help monitor glucose. The results was a had a better diet, lost weight and my labs showed my MGUS stopped getting worse. After that I kept taking high doses of curcumin but of vacations I was eating out and not controlling my diet or monitoring my glucose. I just got my most resent Labs back and they are not good at all. I may even be in WM range. I'll know after I get a BMB this weekend and see my Hemo/Oncologists after the BMB results are back. I'm now thinking the only reason my March labs did not show progression was do to my better diet. My plain now is to get my BMI under 25 as shown in this study.... https://pubmed.ncbi.nlm.nih.gov/35440099/
If this doesn't work, I'll probably being treated for WM at the end of 2025.
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@dcuste
Good morning. Please keep us updated with your BMB results. I have also had IGM Lambda for 4 years and although my light chains, CBC and complete metabolic panel are normal, my IGM continues to climb 100 points a year and is now in the 700+ range. Just had a viscosity blood test last Monday (checking paraproteinanemia) and it was also normal. My most recent IGG was normal but IGA and IGG have been low since diagnosis. The hematologist didn’t seemed very concerned a year ago and said my numbers were much better than most of his patients. When I mentioned last Monday that his other patients had IGM in the thousands, he said “yes, and that’s when it’s scary” Unfortunately I am unable to tolerate high doses of Qunol Turmeric/Curcumin. I get very weak and tired and the only thing I can think of is I am borderline anemic and it is blocking absorption of iron, even taking it away from an iron supplement. We are in the process of moving to the Corpus Christi area in Texas to be closer to family and when I get settled I am going to find a naturopathic oncologist and see what can be tried.