My husband has been having Lanriotide injections every 28 days for 2 1/2 years. He is Stage 4 with tumors throughout his skull and body. He had 1 tumor removed 30 years ago when there were no medication options. He has minimal side effects. The first week after injection, he isn't very hungry and has a hard time eating. However, he does everything he wants to do -- golfing daily, 120 pushup/day, 30 minutes on a stationary bike. Really the only issue is not likely most food and not being hungry. He takes enzymes to help with digestion which definitely makes a difference.