Yes! My daughter was diagnosed about 6 years ago after testing for Crohn's and other digestive disorders. She is doing really well on the daily meds. I have mentioned mast cell activation several times on this thread but don't get much response. There simply are not enough doctors who know what it is. They diagnose Sibo and IBS (which I think is just a symptom of an underlying diagnosis). There is a good deal of info online with a google search. What was the specialty of the doctor who diagnosed your grandson?