Can anyone share their experience with Nubeqa (darolutamide)?

Is anyone here have heart disease while taking Nubeqa?
I normally don't have problems but have had some palpitations lately. I've been exercising fairly strenuously with no problems. What side affects have others here have if you can to mention it.

Thanks

My husband started it exactly a month ago. He says he feels fine. He has had a few hot flashes but none are terrible…he calls them warm flashes. He had the 6 month Lutron a week before he started Nubeqa. His PSA went from over 400 to 70 the first 3 weeks. He was diagnosed with advanced prostate cancer with many bone metastasis on his pet scan. His psa test in 2023 was normal. In 2024 he missed the psa. In early 2025 it was over 400. We were blindsided. We are very optimistic. He is 73. Good luck and keep the faith💕

I've been taking Nubeqa for 2 months. I've been a heart failure patient for years. No issues yet. Heart enzymes bloodwork a week ago came back normal.

I was diagnosed on my Birthday in the hospital. I turned 60 years old.

Thank you so much for your response. I've only been on Nubeqa for about 2 months. Haven't had heart enzymes checked; guess I need to ask my cardiologist about that.
Thanks again hope you have a good day

I was in the 4% which had allergic reaction with head to foot hives. Doctor advised cutting dose back but still had reaction.

Im sorry to hear that; it's gotta be awful. I feel funny on it and makes me have mood changes which is hard. Can you take benadryl for the allergic reaction.

I am 2 weeks in on Nubeqa, loving it. I feel great with a twist. My energy level is wonderful. My PSA, not so wonderful. Lofty expectations. Feeling great, walked into first oncology appointment 2 weeks after starting Nubeqa, waiting for labs, thinking how low will my PSA go. Labs came back, heart sunk, PSA went up from 17 to 23. Dang. Advanced prostate cancer guys like me can't spend too much time in sadness, we simply don't have the time. Within an hour my positive energy returned, enjoyed time with my family on the ocean, Hood Canal.

Oncologist office/MyChart set up 10 radiation appointments for me next week. Speaking of radiation. I volunteer on a prostate cancer research panel every two months at Fred Hutch Cancer Research Institute in Seattle. We meet today. Life is good

"Thanks again hope you have a good day"

You're welcome and since I'm still on the right side of the grass, I'll have a great day!😁

I’m 73, in 7th month taking Orgovyx and completed 44 radiation treatments in the spring. All the best!