@dmdinapoli81
https://pmc.ncbi.nlm.nih.gov/articles/PMC9096784/
I have posted a link that I thought was interesting showing a possible link of MGUS to infections, autoimmunity and inflammation. Here is my opinion. When the body is under constant inflammation due to whatever source, disease can set in. I had Inguinal hernia surgery in 2017 with a mesh patch and have had recurring pain in that area since. I consulted a surgeon since who stated that the body recognizes the mesh patch as foreign and forms scar tissue around it. Some people’s immune system react to this foreign material (remember the issues with silicone breast implants?) and constant inflammation sets in. My MGUS was diagnosed in 2021 although I knew something was amiss in my body 2-3 years prior to that. So I believe we need to do everything we can in regard to diet, exercise, sleep and healthy living (no sugar, smoking, alcohol, processed foods etc) to alleviate inflammation in our bodies especially as we age because our detoxification system doesn’t work as well. I decided to go ahead with a bone marrow biopsy and full skeletal and organ scan because of the connection of MGUS to lesions and disease in the body. So far my bone marrow biopsy and full skeletal CT are normal and I am having the full body CT in 2 weeks. I agreed to these diagnostic procedures because my MGUS markers have not stabilized since 2021 and are gradually moving out of range although my hematologist stated that my markers are better than most of his other MGUS patients. So it makes sense to me that MGUS (constant inflammation) can contribute to increased risks of other disease.