@puzzled211
It is confusing and there is a lot of literature out there to read. This was helpful to me about smoldering MM.
https://cancerblog.mayoclinic.org/2025/04/22/smoldering-multiple-myeloma-what-it-is-how-it-progresses-and-the-latest-research/
They are making new discoveries all the time, and there is good research going on. The treatment of multiple myeloma has advanced significantly in the last decade. I have MGUS, but when my physician visits with me every six months and goes over my lab results, he always ends our meeting by saying “don’t worry, if this ever advances to multiple myeloma, it is very treatable.” That gives me a lot of confidence to just be able to live my life and not suffer dread every day. Only 10% of patients with MGUS will ever advanced to multiple myeloma.
I hope these discussions are helpful to you. Will you check back in and let us know how you were doing?