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Husband’s low psa, aggressive Gleason 8
Prostate Cancer | Last Active: Jul 27 2:32pm | Replies (35)Comment receiving replies
This the first i have heard of neuroendocrine prostate cancer, and the potential for morphing. I will do a little research, but can you provide more info on this?
Im trying to dig in to treatment options - have cribiform morphologies and 93 Decipher. had RP 6/18, hopeful, but realistic about recurrence. 4+3 (without factoring in Cribiform), EPE, but clean margins, pelvic lymph nodes and vesicles. Clean PET. So little info (that I can find) on cribiform/IDC treatment plans.....but the good news is there looks to be a lot of potential solutions.
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I know two people who ended up with neuroendocrine prostate cancer. Neither of them lived more than about a year after diagnosis.
One guy went to Austria to get Pluvicto and actinium, He went on a PARP inhibitor but nothing helped.
The other person had chemo that included carboplatin, It helped a little but not much. He tried to get into one of the DLL studies, but he was too weak By the time he was in consideration. They had closed one of them to concentrate on women with breast cancer and neuroendocrine.
A study has shown that staying on the same prostate cancer drug for more than four years gives you at least least a 5% chance of neuroendocrine. That includes everything Zytiga, the lutamides and even the ADT drugs.