1. < Prostate Cancer

Hormone Treatment Experience

Posted by mhordes @mhordes, 4 days ago

Had my first visit today at MD Anderson Proton Center and the Dr ordered AlteraAI to see if Hormone Therapy would help

If so he is leaning to Hormone Therapy Light. Not sure what that means? Hormone Therapy does not look like fun!

Anyone have experience with ADT Light or just Hormone Md light? Are the side effects the same?

Thanks for any feedback

Mark H

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jeff Marchi | @jeffmarc | 1 day ago
In reply to @heavyphil "Oh no I was just joking about getting hot flashes from watching the news!😅 My T..." + (show)
@heavyphil

Oh no I was just joking about getting hot flashes from watching the news!😅
My T came back to 688 3 mos after finishing Orgovyx.
Phil

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I should’ve realized that, The way you put it did look a little suspect 😀

Your testosterone sure came back aggressively. Gotta make you feel a little bit better, like normal!! Whatever that is after PC

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1 reply
daveinflorida | @daveinflorida | 1 day ago
In reply to @pjsatz "I believe ArteraAI tells if you are likely to benefit from the addition of Abiraterone to..." + (show)
@pjsatz

I believe ArteraAI tells if you are likely to benefit from the addition of Abiraterone to standard ADT like Lupron or Orgovyx. It compares your cell patterns to a database of cell patterns and outcomes from past studies. From what I understand it is not definitive but another data point to be considered. But the outcome of AteraAI does not affect the decision for standard ADT.

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The results of my ArteraAI test were:

"ST-ADT Biomarker: Positive. On average, patients with this result had significant risk reduction in distant metastasis with the addition short term androgen deprivation therapy."

The report itself says nothing about what type of ADT, and my RO recommended 6 months of Orgovyx, which I agreed to.

I believe you are right in how ArteraAI makes the determination.

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1 reply
pjsatz | @pjsatz | 1 day ago
In reply to @daveinflorida "The results of my ArteraAI test were: "ST-ADT Biomarker: Positive. On average, patients with this result..." + (show)
@daveinflorida

The results of my ArteraAI test were:

"ST-ADT Biomarker: Positive. On average, patients with this result had significant risk reduction in distant metastasis with the addition short term androgen deprivation therapy."

The report itself says nothing about what type of ADT, and my RO recommended 6 months of Orgovyx, which I agreed to.

I believe you are right in how ArteraAI makes the determination.

Jump to this post

Oh, ok, thanks. I didn’t realize, they may have different focus of report based on what they find, makes sense.

Thanks,

Phil

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heavyphil | @heavyphil | 1 day ago
In reply to @jeffmarc "I should’ve realized that, The way you put it did look a little suspect 😀 Your..." + (show)
@jeffmarc

I should’ve realized that, The way you put it did look a little suspect 😀

Your testosterone sure came back aggressively. Gotta make you feel a little bit better, like normal!! Whatever that is after PC

Jump to this post

Yes, much better physically but always worried that all that T will be food for you know what!

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seasuite | @seasuite | 15 hours ago

I took just 4 months of Orgovyx that completed about 1.5 years ago. I eat well, exercise daily and play pickleball and golf. After one year, my Testosterone did not fully recover and my team agreed that I could take supplements. My fertility RO prescribed TGel and Cialis. My T returned to normal and I'm in the process of weaning off both drugs. My PSA was stable during this time.

Compared to many others, 4 months is 'ADT light'. Sadly, I still have not recovered from the main 4 side effects: Belly Fat (gained 10 lbs. eating a healthy Mediterranean diet and drinking less); Hot Flashes: definitely still happening; Energy/Strength: struggle to run (5-10K) distances as I could before ADT; ED: about 80% of normal.

I'm trying to understand how these side effects could still be so active when I clearly had a 'light' version of ADT. I'm meeting one of my Dr. team on Monday and, if I don't get a suitable reply, I'll check with some of my other doctors. The literature on this topic is all over the map, hence, not useful. (Disclaimer: I'm grateful not to need more intense treatments at this time...just want to understand what's going on and maximize QOL like we all do).

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