You can the main number at the Mayo tell the operator you would like to speak to someone about your upcoming appointment the maim number is 1 507-284-2511. The operator will connect you with someone who can answer your questions.
Today things can travel by Internet.
Are you traveling and will you need a hotel room? Basically, every hotel in Rochester has shuttles so you don’t have to drive if you choose to live a mile or two away. Traveling downtown right now is a mess as there is a number of major construction projects going on.
If you are driving, go to a website called Mail construction through the drop-down and choose the building. You have your appointment in. It will tell you where to park.
Good luck