Concerned about the side effects of anastrozole

Posted by tinalove @tinalove, Jan 31, 2016

I completed all treatments for breast cancer but now I am supposed to take hormone blocker, named anastrozole. im concerned about the side effects. Has anyone here taken it and did anyone have hair loss?

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@otas

Hello srkellen,
I can totally understand the side effects you’re going through. I have been on Anastrozole for the past 2 years. I definitely have developed some mood issues, depression and anxiety.
I have also been diagnosed with osteopenia, high blood glucose & cholesterol which I never had before taking Anastrozole. I’m also experiencing extreme hair loss. And it seems nothing can be done for any of these side effects.

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There are plenty of things you can do for these symptoms. Take more meds! They’ll give you Celebrex for joint pain, bp meds, lexapro, Ativan and a bunch of other stuff. There’s no winning with AIs.

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@beachbabe

Has anyone had any increase in blood pressure and/or any cardiac issues while taking Anastrazole?

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Oh yes.....before starting treatment on an AI I had moderately high blood pressure, say around 140-150's, handled by drugs. The first AI I tried to reduce my chest wall tumor, Anastrozole, make it go up into the 160's & I had to add another BP drug. Doc switched me to Letrozole, which didn't seem to be raising it so fast. But 4 months in I started getting occasional "spikes" in BP at night up to 170. By the next month it was becoming spikes up to 190 even 200 nearly every night! I was visiting the ER. I told the Doc I was off all AI's & stopped. They threw me into "labile hypertension" which I still have & even with new drug Fulvestrant, I have to monitor my BP 8 times a day, and take a quick acting drug if it goes over 170. I am not a good candidate for hormone blockers; but the Fulvestrant is working well to shrink my tumor.
I've read that those with CVDisease should not be on AI's .
Patty

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