Hormone Therapy

If you have residual cancer cells in the prostate area, that means that after prostate removal you had positive margins.

When that happens, radiation should be arranged to zap the areas that have positive margins.

Going on Elgard will stop it from growing, But if you have not had radiation, you need to Get a second opinion from an expert. You need to find a center of excellence or a Genito urinary oncologist. They will look at your case and make major changes.

Going on Elgard does not kill the cancer. It just stopped it from growing while you’re on it. If you don’t get another Eligard shot, you could be assured that cancer is going to start spreading.

I cannot understand what kind of doctor would leave you in this precarious situation.

Apart from the Eligard, I am currently on radiation therapy, today will be session 19 out of 25 and I am ready for the last session. The radiation has affected my lower intestines, I am having diarrhea almost daily, my hemorrhoids are killing me, and just an overall malaise feeling. I have just a few sessions left so I am going to finish with the Lord's help. Thanks for your comments.

I had radiation for seven weeks. IMRT. That was about 12 years ago. I just never had any side effects from it. It was over a longer time than yours, they spread the daily dosage over a longer period. I know some people back then said they were tired after the radiation, but I didn’t hear from people, that long ago, that had diarrhea.

These days they do it in a shorter period of time and it is tough on some people. I’ve heard of the diarrhea problem, others have it.

Did you have a SpaceOAR or equivalent put in before having radiation?

If you search for diarrhea at the top level, you might be able to find messages that discussed solutions people have found.

I've been on Orgovyx 2 1/2 yrs. My doctors want me to come off it.

I've had surgery, salvage pelvic radiation, and ADT (Orgovyx). PSA < 0.01 for over 2 years (since radiation + starting ADT). I was stage 4a, Gleason 9, Decipher .99 so aggressive. I've got a small lung nodule < 6mm and stable. Probably not cancer but I'm afraid if I stop the Orgovyx and it is cancer that it might start to increase.

I've experienced muscle weakness, joint pain, trouble sleeping, and no energy, overall tiredness-- don't know if this is due to the Orgovyx or not.

I'm scared to stop taking it. I don't mind the ADT side effects although it's been getting worse. I suppose my doctors are worried about possibly more serious SE's like bone loss/weakness and heart problems. But all this sounds better than my cancer getting worse.

Drs apparently just think I've been on it long enough and I suppose I'll become CR eventually? Don't want that. But, it's scary to stop, not knowing what might happen.

A Gleason, 4+3 does not call for two years of ADT. But after a relapse and salvage radiation, this is the following information that the NCCN provides.

Key points from NCCN and recent evidence:

24 months of ADT with salvage radiation improves outcomes for men with adverse features (including Gleason 4+3).

Shorter durations (e.g., 6 months) have not shown the same survival benefit as 24 months in this context.

The decision may be individualized based on other risk factors, side effect tolerance, and patient preference, but 24 months is the standard for higher-risk cases per NCCN.

Going to get salvage radiation, the 5 day treatment, starting next week, one every other day. They want me to start ADT. Just wondering how Orgovyx worked for you? One of my RO said that I could wait a month or two to without ADT and see where PSA is headed. Any thoughts on that?

I haven’t got salvage radiation yet, start next week, the 5 day every other day treatment instead of 6 weeks. No ADT….. yet.