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First PSA test after radiation for intact prostate?

Prostate Cancer | Last Active: Dec 1 7:00pm | Replies (24)
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Profile picture for toolbelt @toolbelt

I asked my RO what he expected my first post SBRT PSA to be.....he said "lower". The first PSA is rather meaningless. It can take up to 24 months for the PSA to reach a nadir. (lowest value). And some research shows a longer time to nadir as having being a prognostic plus. As beammeup said, and the definition of BCR is, a PSA of 2.0 above your nadir.
It is a long ride. It is a trying, worrying ride. It can literally be a "bouncy" ride. But we have to be patient, see where we are, and where we are going on that ride.

Stay Strong Brother, We Got This.

Pre-treatment PSA 7.8. SBRT completed 12/28/2023
3/28/2024 0.09 (While still on Orgovyx)
6/28/2024 0.19 ( Three weeks post-Orgovyx)
10/17/2024 0.59
1/8/2025 0.62
3/20/2025 0.65
5/21/2025 0.47

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Replies to "I asked my RO what he expected my first post SBRT PSA to be.....he said "lower"...."
vircet | @vircet | Jul 13 7:03pm

If I understand this correctly:
Your nadir while still on Orgovyx was 0.09
Three weeks post-Orgovyx it was 0.19 (I suspect at this point, Orgovyx has not yet been totally flushed out of your system)In the 4th, 7th, and 10th month (approximately), with the med totally out of your system, your average PSA was in the low 0.60s, no doublingIn the 12th month post-Orgovyx, PSA was trending down to under 0.50
Regardless of what your actual nadir was, you're far from seeing a rise of 2.0 above nadir.
Even if you did not reach yet the ideal nadir of < 0.2, I think you are all good. If I can somewhat duplicate your experience, I will be so happy.
Congratulations. (Do update us as your PSA trends down closer to 0.2

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