In my case, it took about three months for my PSA to go down from 67.9 to undetectable (< 0.01) after I started on ADT + Apalutamide (Erleada) in 2021. It has stayed undetectable since

My cancer was already at stage 4b with a single large metastasis to my spine (so assume I would have been Gleason 8 or 9 and Decipher close to 1.0).

I had debulking surgery and post-op radiation to my large spinal metastasis in 2021, and then 20 fractions of radiation (SBRT) to the prostate itself 6 months later. We hit the cancer early and hard: so far, no sign of recurrence. 🤞