In reply to Michaela’s: yes I am taking bukinsa and the abdominal pain and trouble started a while after I started taking it. Haven’t had constipation this bad ever before but now taking stool softeners daily and psyllium capsules every day, which helps some. Other symptoms similar to yours but the back pain has been a bit better while muscle aches and joint pain is worse. Good news is my IgM continues to go down but at this point very slowly. Still good news though. Leg cramps are better with magnesium supplements but cold a lot and also tired easily. I guess I can tolerate most of it as long as it continues to work on the Cancer. Longing for the day when I can quit though and get back to normal hopefully. Good luck to you and hang in there. We can beat this.