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← Return to Firm lymph node + low WBC for 1 year — could it be lymphoma?
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Firm lymph node + low WBC for 1 year — could it be lymphoma?
Blood Cancers & Disorders | Last Active: Jul 11, 2025 | Replies (7)Comment receiving replies
I have done two CRP tests several months apart.
The first one was in September 2024, and the result was 3.8 mg/L.
The second one, done recently, showed a result of 3.15 mg/L.
Both results seem to suggest a low-grade chronic inflammation.
I don’t have any signs of acute infection at the moment.
In addition, I had Toxoplasma testing done twice. Both results showed IgM negative and IgG positive, which indicates a past infection, not an active one.
I also had a full viral panel, which came back normal.
Could this ongoing inflammation be related to my persistently low white blood cell count and the stable lymph nodes I’ve had for over a year?
I’m wondering whether this could be immune-related or worth further investigation with a hematologist.
Replies to "I have done two CRP tests several months apart. The first one was in September 2024,..."
Yes it probably is I have beef two years now
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Hi @ahmg. Yes, having chronic underlying inflammation can be a cause of a low white blood cell counts, which in turn weakens the immune system and your ability to fight infections. Considering you’re 25 and have a long life ahead of you, it might be a good idea to find the underlying cause of this inflammation and why you have these persistent swollen lymph nodes. Having a low WBC isn’t always a sign of a medical problem but it’s good to have it checked out.
Conditions such as an autoimmune disease, low Vit D level, food and mold sensitivities, low hormone levels, yeast infections, lymphoma, leukemia, other blood disorders, etc., can be potential culprits for low WBCs. So it may take some sleuthing.
You could start with your PCP instead of a hematologist to see if there are other blood tests, imaging, perhaps a biopsy of a swollen lymph node to narrow down the cause. If this is related to an autoimmune disease you may be referred to a rheumatologist.
I have the feeling that this is troubling you and you’d like to get to the bottom of the issue. So start with your primary doctor and take it from there. Does this make sense?