The Tymlos people are wrong. The pen is not set to 80. It's set to zero. You have to turn it, "click" it, until the little window reads 80; that is as far as it goes. What they aren't telling you is that each little click equals 10. Eight clicks equals 80. Once you inject, it goes back to zero, and you start over the next day. I've been using Tymlos for 15 months - I can see that pen in my sleep. 🙂

The issue is that only the full dose of 80 was tested, so that is what they are telling you. That doesn't mean a lower dose isn't effective. A number of people here use a lower dose because they can't tolerate 80.

After 15 months, my abdomen is fine. It's not like you can see 400 marks. The needle is very thin. I rotate - I have four areas on each side, and I just alternate left and right.