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Waldenstrom macroglobulinemia: What can I expect with chemo?
Blood Cancers & Disorders | Last Active: 1 day ago | Replies (34)Comment receiving replies
Hi @travelmom4 ,
[I was dx'd with SMZL, WM, and CLL.]
I have an IgM of 2350, IgG 320, IgA of 25. I've only been on Zanubrutinib since I was dx'd last May. I had a few very slight lymph nodes swelling & a slightly enlarged spleen. While being on Z didn't impact those numbers much, my platelets went from 99 to 176, and the vast majority of my blood tests are now all in the normal range. It seems to be working fine at this point. Other WM-specific test - my Kappa FLCs dropped from 12 to 8, and my leukocytes went from 47 to 5.
At my next appt (this month) we will discuss the benefits of adding a BCL2 inhibitor or an anti CD20 monoclonal antibody "to deepen the response".
Replies to "Hi @travelmom4 , [I was dx'd with SMZL, WM, and CLL.] I have an IgM of..."
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Wow! I’m so sorry to hear everything you’re going through. Thank you so much for your reply. There just isn’t much information out there about high IgM that I’ve found.. I really appreciate your share. Wish you all the best and good health. I’m hoping that my IgM being high is just a fluke or virus. I’ve been sick with GI issues for a while.. I had a total Colectomy in 2023 and melanoma in 2019 . Thank you again