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Waldenstrom macroglobulinemia: What can I expect with chemo?
Blood Cancers & Disorders | Last Active: Jul 5 11:10pm | Replies (34)Comment receiving replies
Thank you for your reply. I’ve been trying to connect with others with High total IGM mine is 727 with a low igg dr referred me to hematology oncology and have apt in 2 weeks. Trying to get info so I have my questions ready.
Any info or your own experience would be greatly appreciated. Hope you’re feeling ok and well
Replies to "Thank you for your reply. I’ve been trying to connect with others with High total IGM..."
My IGM is 2250. It's been rising for 2 years since my diagnosis. I had a bone marrow biopsy.
Marginal Zone Lymphoma is rare and slow growing. I've been on wait and see but now my symptoms are horrible. Fatigue,weight loss, shortness of breath. So I start Rituximab tomorrow.
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Hi @travelmom4 ,
[I was dx'd with SMZL, WM, and CLL.]
I have an IgM of 2350, IgG 320, IgA of 25. I've only been on Zanubrutinib since I was dx'd last May. I had a few very slight lymph nodes swelling & a slightly enlarged spleen. While being on Z didn't impact those numbers much, my platelets went from 99 to 176, and the vast majority of my blood tests are now all in the normal range. It seems to be working fine at this point. Other WM-specific test - my Kappa FLCs dropped from 12 to 8, and my leukocytes went from 47 to 5.
At my next appt (this month) we will discuss the benefits of adding a BCL2 inhibitor or an anti CD20 monoclonal antibody "to deepen the response".