You’re right. No one really knows what the affects of these drugs are going to be in the future. I think that if a person has an underlying condition, the drugs will effect them differently. I didn’t even know what MGUS was a year ago. Waygovy gave me intense Diarrhea and constipation. It was hurting me and when I stopped it, I no longer have this gut problem that was unbearable. I liked losing the weight but I’m doing it on my own with exercise and control. I’ve lost more weight now properly then on the Waygovy. I am watching what I eat because I’ve become allergic to dairy and other foods. Someone said that there was a study done at Farber and Waygovy does not interfere with a person having MGUS. I’m not so sure about that because the drug hurt me. I really appreciate everyone’s input though. I just want to get to the bottom of what’s going on with my health and whatever it is, treat it properly….